Tony Palladino claimed a maiden List A five-wicket haul, but it was in vein as Lancashire claimed victory at The 3aaa County Ground.
Derbyshire were unbeaten in three matches but a target of 301 proved beyond them as Wayne White took 4 for 33 to bowl out the hosts for 199, with skipper Wayne Madsen top-scoring with 49.
Lancashire’s total of 300 for 8, which was their highest against Derbyshire in one-day cricket, was built around half-centuries from Ashwell Prince, Karl Brown, Alex Davies and Steven Croft with Palladino returning his best limited overs figures of 5 for 49.
The Falcons lost early wickets and when Madsen was fifth out to White with 200 still needed, the game was up.
Lancashire’s innings started slowly with only 49 coming from the first 10 overs powerplay for the loss of Australian Test batsman Usman Khawaja. He made 31 from 28 balls against his former county before Mark Footitt found some late movement and bounce to have him caught behind.
Derbyshire suffered a blow when Taylor injured his left ankle two balls into his sixth over and had to be helped off the field and Lancashire gradually increased the tempo with Prince and Brown adding 61 in 15 overs.
Prince was bowled for 57 trying to sweep David Wainwright and Brown also failed to go on when he was caught behind for 59 off a bottom-edged pull against Palladino in the 32nd over.
Lancashire lost skipper Paul Horton in Palladino’s next over when he was caught at point off a ball that stopped on him, but Alex Davies lifted Footitt over the wicketkeeper’s head for the first six as he and Croft accelerated in the last 10 overs.
Croft drove and pulled Wes Durston for successive sixes before Palladino halted the charge by having him caught at deep square leg for 51 from 42 balls and then yorking Davies for 53 with the next delivery.
Derbyshire’s chase started badly when the dangerous Durston was lbw playing back to Bailey who struck again by tempting Scott Elstone into a wild drive at a wide ball with only 28 on the board.
When Billy Godleman also fell to a reckless cut at Jordan Clark and Marcus North top-edged to backward point trying to pull White, Derbyshire’s hopes rested with Madsen who moved smoothly to 49 from 37 balls.
But when he tried to launch White over the deep square leg boundary and only picked out Brown who made no mistake, his exit signalled the end of the home side’s chances.
Alex Hughes straight-drove Simon Kerrigan for six on his way to 47 off 54 balls, White bowled Footitt to complete an efficient display by the visitors with 57 balls still remaining.
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